Abstract There is accumulating evidence cnd field fox of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).In this paper we deduce the pathomechanisms resulting in central nervous pathology and the myriad of neurocognitive symptoms.We outline tentative mechanisms of impaired ce
Abstract Rad51 maintains genome integrity, whereas Rad52 causes non-canonical homologous recombination leading to gross chromosomal rearrangements (GCRs).Here we find that fission yeast Srr1/Ber1 and Skb1/PRMT5 promote GCRs at centromeres.Genetic and physical analyses show that srr1 and skb1 mutations reduce isochromosome formation mediated by cent
This paper presents a regional 3D geological modeling method based on the stacking ensemble technique to overcome the challenges of sparse borehole data in large-scale linear underground projects.The proposed method transforms the 3D geological modeling problem into kit purge campagnolo a stratigraphic property classification problem within a subsu
Introduction: India is home to the largest population of orphaned children in the South Asia, who are at increased risk of poor psychosocial well-being.In the Indian context, literature on the psychosocial well-being of orphans and vulnerable children (OVC) is scarce.Our research was aimed at fulfilling this gap by understanding self-reported psych